How sleep loss rewires your brain for cravings and weight gain

Summarised by Centrist

Poor sleep doesn’t just make you tired, it pushes your brain and body toward weight gain, insulin resistance, and junk food addiction, says neurologist Joanna Fong-Isariyawongse.

Even one night of short sleep disrupts your hunger hormones: ghrelin (which makes you feel hungry) goes up, while leptin (which signals fullness) drops. At the same time, your brain’s decision-making centre slows down, while its reward circuits light up in response to high-calorie foods. In other words, your brain becomes worse at saying no and more tempted by fat and sugar.

Lab studies show people sleep-deprived for just one night crave junk food more, rate it as more desirable, and are more likely to eat it, even if they aren’t particularly hungry. As Fong-Isariyawongse puts it, “This isn’t just about willpower. Your brain, short on rest, is nudging you toward quick, high-calorie fixes.”

Sleep loss also lowers insulin sensitivity by up to 25%, increasing your body’s tendency to store fat and raising your risk of Type 2 diabetes. It elevates cortisol, the stress hormone linked to abdominal fat storage, and disrupts your body’s natural metabolic rhythm.

But there’s good news: “Just a few nights of consistent, high-quality sleep can start to rebalance appetite signals, improve self-control, and stabilise metabolism,” she writes.

If you’re reaching for snacks after a rough night, it’s responding to fatigue. The fix isn’t another coffee or crash diet. It’s sleep.

Read more over at StudyFinds

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